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Can I use Doxycycline antibiotics daily as prevention for syphilis, gonorrhea or chlamydia?

The short answer is no, you can’t use Doxycycline antibiotics daily to prevent syphilis, gonorrhea or chlamydia.

Currently, there are research studies and clinical trials digging deeper into your question. It looks like researchers are still exploring issues like how to avoid antibiotic resistance, possible side effects of daily antibiotics and determining which populations might get the most benefit of this type of strategy. So while researchers are working on future preventative medication options to add to the STI prevention “toolbox”, we recommend tools we know can be effective.

Tools to prevent sexually transmitted infections like syphilis, gonorrhea, and chlamydia:

  • having conversations with your sexual partner(s) about what safer sex means to you
  • getting tested on a routine basis for STIs
  • STI treatment to manage or eliminate infection
  • condoms and internal condoms
  • using water-based lube with condoms
  • reducing the number of sexual partners
  • choosing types of sex that less commonly pass STIs
  • using new drug equipment that is never shared, and disposed of properly